B65-B83: Helminthiases

B74: Filariasis

Filariasis refers to a group of infectious diseases caused by parasitic worms, filariae, which are transmitted to humans through the bites of infected mosquitoes. These microscopic worms typically reside in the bloodstream, where they can live for several years. After penetrating into the human body, they begin reproducing, leading to an overpopulation and buildup in the blood and lymph vessels. Common symptoms of filariasis often take time to surface, but may include swelling in the legs, arms, genitalia, and breasts in the later stages. This is due to the filariae blocking the body's lymphatic system, the network responsible for circulating proteins and immune cells. In some severe instances, the disease can also result in significant skin alterations and immune responses, a condition known as 'elephantiasis' due to the notable thickening and hardening of the skin. The progression of the disease is slow, but filariasis can cause considerable damage to the lymphatic system and kidneys over time.