B21.1: HIV disease resulting in Burkitt lymphoma

HIV disease resulting in Burkitt lymphoma (ICD-10 code B21.1) is a specific medical condition where a person's HIV infection leads to the development of Burkitt lymphoma, a type of non-Hodgkin lymphoma. In such cases, an individual's immune system is weakened by the HIV virus, making them more susceptible to certain cancers. Burkitt lymphoma is a fast-growing malignancy that primarily involves cells in the immune system known as B-lymphocytes. HIV-associated Burkitt lymphoma often presents with symptoms such as unexplained weight loss, night sweats, and swollen lymph nodes, particularly in the neck, armpits, and groin. The malignant cells can spread quickly throughout the body and affect other organs and systems. It's important to note that having HIV doesn't necessarily mean a person will develop Burkitt lymphoma, but the risk is significantly higher than for someone without HIV. This condition exemplifies the complex relationship between immune function and cancer development.