B21: Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms

B21.0: HIV disease resulting in Kaposi sarcoma

HIV disease resulting in Kaposi Sarcoma, coded as B21.0 in ICD-10 WHO 2016 classification, is a condition where a person diagnosed with Human Immunodeficiency Virus (HIV) develops a type of cancer known as Kaposi Sarcoma (KS). HIV is a viral disease that weakens the immune system's ability to fight infections and diseases. Kaposi's sarcoma is a cancer that develops from cells lining lymph or blood vessels. It often produces visible purplish lesions on the skin, but it can also affect other body systems. HIV-related KS tends to be more aggressive than in individuals without HIV. The cancer's onset may coincide with or follow the presentation of other illnesses associated with HIV, as the inevitable decline of the immune system makes the body vulnerable to opportunistic infections and cancers. Symptoms of KS may vary depending on the parts of the body affected, but common presentations include patches or lumps on the skin, respiratory problems, or gastrointestinal complications.