A50-A64: Infections with a predominantly sexual mode of transmission

A52: Late syphilis

Late syphilis refers to a stage of the sexually transmitted infection caused by the bacterium Treponema pallidum. This stage typically occurs years after the initial infection and can involve multiple organ systems including the brain, nerves, eyes, heart, blood vessels, liver, bones, and joints. Patients may not experience symptoms during this stage, or they may suffer from very severe health problems. Symptoms can vary widely, from damage to the skin, bones and soft tissue, to more serious complications like inflammation of the blood vessels (which can lead to aneurysms and other major health issues), and neurological problems like stroke and meningitis. There can also be mental health implications, as the infection can lead to changes in personality, mood, and behaviour. It is caused by not receiving appropriate treatment in the earlier stages of the infection.